XEOMIN® (incobotulinumtoxinA)
carries a boxed warning.
As with all neuromodulators,
there is a risk of spread
from the area of injection
and life-threatening symptoms.
Reconstituting XEOMIN
You will need a clean workspace,
your alcohol wipe,
diluent saline,
and three types of syringes.
Next, find your XEOMIN vial,
available in 50, 100, or 200 Unit doses.
For additional injection information,
consult section two in the Prescribing Information.
Select a dose of XEOMIN and inspect the vial.
XEOMIN is a sterile, white to off-white powder,
before reconstitution.
Use saline to reconstitute XEOMIN.
Clean the rubber stopper
of both the saline and XEOMIN vial
with an alcohol wipe.
Important: Do not pry or pop the cap off of the XEOMIN vial
as it is vacuum-packed
and doing so may result in XEOMIN powder
dispersing into the air.
Draw the desired volume of saline into the syringe,
then vertically insert the needle into the XEOMIN vial.
The vacuum within should draw most of the saline
into the XEOMIN vial.
If the vacuum is not present,
the XEOMIN vial should be discarded.
Gently inject any remaining saline.
For diluent volumes and instructions,
including reconstitution of volumes
greater than five milliliters,
consult table 5 in the Prescribing Information.
After the needle is removed,
the XEOMIN vial should be swirled and flipped to mix.
All powder should be dissolved into the saline.
Reconstituted XEOMIN should be clear, colorless,
and free of particulate matter.
Reconstituted XEOMIN should be used
for only 1 injection session,
and for 1 patient only.
To view details on
intramuscular and intraglandular injection,
consult the Prescribing Information.
Reconstituted XEOMIN can be used
up to 24 hours after dilution
if stored in a refrigerator
between 2 to 8 degrees Celsius.
For more information about XEOMIN,
including Important Safety Information
and BOXED WARNING,
visit XEOMIN.com.