All images in this section are for illustration purposes only. Not actual patients or caregivers.

All images in this section are for illustration purposes only. Not actual patients or caregivers.

Upper Limb Spasticity (excluding spasticity caused by
cerebral palsy) in Pediatrics

XEOMIN for Upper Limb Spasticity,
Excluding Spasticity Caused by Cerebral
Palsy, in Pediatrics

In children with upper limb spasticity, there is an imbalance of signals from the brain to the muscles, which causes stiffness and spasms. This can lead to abnormal arm or hand positions, uncomfortable movement, and pain.1

XEOMIN is injected into muscles to help interfere with these signals. This helps decrease muscle stiffness and improve your child's ability to function using the affected muscles.2

Some stiffness and spasms may still occur, but in most patients less severely.

Images are for illustration purposes only. Individual results may vary.

XEOMIN Helps Improve Upper Limb Spasticity Symptoms

In clinical studies, XEOMIN improved muscle tone and resulted in functional improvements 4 weeks after initiation of treatment2*

Of patients treated at 8 Units/kg
experienced a 1-point change or
greater on the Ashworth Scale2

Mean improvement at Week 4 in
GICS score for patients treated at
8 Units/kg2

Of patients treated at 2 Units/kg
experienced a 1-point change or
greater on the Ashworth Scale2

XEOMIN provided sustained, long-
term improvements in muscle tone
for all upper limb muscle groups
over 56 weeks (4 injection cycles)2†

*Functional improvement was measured using the Global Impression of Change Scale (GICS), a global measure of a patient's functional improvement.

†Clinical patterns treated were flexed elbow, flexed wrist, forearm pronators, clenched fist, and thumb-in-palm over 4 injection cycles.

Does this seem familiar?

Michael* is a 6-year-old with
upper limb spasticity

*Images and fictionalized story are for illustration
purposes only. Not an actual patient.

References

  1. Ozcakir S, Sivrioglu K. Botulinum toxin in poststroke spasticity. Clin Med Res. 2007;5(2):132-138.
  2. XEOMIN® [Package insert]. Raleigh, NC: Merz Pharmaceuticals, LLC; 2021.